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2023PurquerioBM_deMoraesTF

  

Invention (Patent): Purquerio BM, Fortulan CA, Botega R, de Moraes TF. Prótese cirúrgica antiluxação e sistema artificial de ligamento redondo da mesma. BR102015006381B1 (Antiluxation surgical prosthesis and artificial round ligament system thereof, 2023). Translated from Portuguese.

 

BR102015006381B1 Brazil

Inventors: Benedito De Moraes Purquerio, Renan Botega, Thiago Francisco De Moraes, Carlos Alberto Fortulan

Worldwide applications 2015 BR

Application BR102015006381-4A events:

2015-03-23 Application filed by Universidade De São Paulo - Usp.

2015-03-23 Priority to BR102015006381-4A

2016-09-27 Publication of BR102015006381A2

2023-04-11 Publication of BR102015006381B1

 

Antiluxation surgical prosthesis and artificial round ligament system thereof

Benedito De Moraes Purquerio, Renan Botega, Thiago Francisco De Moraes, Carlos Alberto Fortulan

 

Abstract

The present invention relates to an anti-dislocation surgical prosthesis in ceramic and/or polymeric materials, porous, multidense and in functional gradient for orthopedic arthroplasty surgeries for resurfacing spheroid or condylar ends of long bones, for example, the hip, of humans or animals. of any size, who present any synovial joint diseases. Said prosthesis is made up of three parts: the femoral head, which can be of various sizes, the femoral guide-pin in one size or according to the femoral head, and the pelvic acetabulum, which may be of various sizes in correspondence with the head. femoral. Due to its versatility, such a prosthesis can be used in hospitals, orthopedic and veterinary surgery clinics, or similar institutions.

Description

FIELD OF THE INVENTION

[1] The present invention is part of the field of medicine, more specifically in the area of prostheses and surgical implants for orthopedics, and describes an anti-dislocation surgical prosthesis in ceramic and/or polymeric materials, porous multidense and in functional gradient for orthopedic arthroplasty surgeries of hip resurfacing, as well as an artificial round ligament system of the referred prosthesis.

[2] In general, this prosthesis can be used for recapping spheroid or condylar ends of long bones in arthroplasty surgeries in humans or animals of any size, which present any kind of synovial joint disease.

FUNDAMENTALS OF THE INVENTION

[3] Resurfacing arthroplasty (resurfacing) of long bones, such as those of the hip, is a technique that provides excellent results in young and active patients, in contrast to conventional long stem prostheses. The choice for the resurfacing prosthesis has been made due to the great advantage of greater post-surgery proximal bone preservation, resulting in greater stability and better physiological movement.

[4] In the state of the art, there are still no consistent records of anti-dislocation surgical prostheses for hip resurfacing in any type of material, which makes the present invention enable safety against dislocation of the prosthesis after arthroplasty surgery from the hip of humans or animals.

[5] Although modern human resurfacing surgical hip prostheses, now manufactured only in metallic materials (metal-on-metal), offer the restoration of the function of the implanted patients, they also present the great and constant risk of dislocation, unavoidable in this type of prosthetic rehabilitation. Furthermore, numerous metallic prostheses used in hip resurfacing arthroplasty are already known, but all of them, without exception, are subject to potential accidental dislocation.

[6] Completely different, in terms of design, from existing hip resurfacing prostheses, the anti-dislocation surgical hip resurfacing prosthesis in ceramic or metallic or polymeric materials, porous multidense, with functional gradient of the present invention presents innovative solutions in relation to its concept of design and materials, as well as their predictability and functional stability with regard to non-dislocation.

State of the art documents

[7] Patent document US2007276364 discloses a hip joint anti-dislocation device and method to prevent displacement of hip arthroplasty implants. The invention prevents displacement by maintaining a retaining tension (coaptation force) on the implant throughout all joint movements. Although this device is used in conventional hip arthroplasty prostheses with the aim of eliminating dislocation in the postoperative period, it presents an inventive concept that is totally different from the present invention, as this document describes an artificial joint capsule as a joint stabilizing element, while that the present invention describes a round ligament as a joint coaptation element.

[8] ITFR990014 describes a post-surgical anti-dislocation prosthesis that can be used bilaterally in hip replacement surgery with second revision prostheses. This prosthesis used, although used in hip replacement, uses the hyperispheric principle (ball-socket) as an anti-dislocation principle, while the present invention describes a prosthesis with a system that allows the replacement of the round ligament, preventing dislocation.

[9] Documents US3067740, EP0655230, EP0485311, FR2210909, W0016960, are cited as a mere understanding of the problem presented, since none of the devices presented are used in surgeries with conventional joint replacement prostheses, and the present invention refers to a prosthesis of joint resurfacing with a system that artificially mimics the functions of the round ligament, when implanted.

[10] Other documents, such as CN202015270 and CN201939550 present orthopedic devices, such as orthoses for use in the postoperative period of hip arthroplasty with the function of preventing dislocation with the use of these devices. These documents presented in the state of the art contribute to the demonstration of the inefficiency of the devices currently used with the purpose of anti-dislocation in the postoperative period.

[11] Therefore, the present invention presents an inventive concept based on a joint biomechanical study, which replaces the functions of the round ligament in order to mimic the joint coaptation force performed under normal physiological conditions.

Advantages of the Invention

[12] The anti-dislocation surgical prosthesis for resurfacing the hip in multidense porous ceramic with functional gradient described in the present invention is an alternative for hip arthroplasty also for patients who have metal allergy problems. Metals in the human body, as is known, in addition to promoting a constant increase in the level of metallic ions in the blood by up to 10 times more in individuals with implants compared to the levels found in individuals without metallic implants, they also cause adverse reactions in patients with allergies. to metals.

[13] Aiming to solve the currently unresolved inconveniences and uncertainties related to the quality of the human body's immune response, as observed in the mentioned documents that use metallic prostheses that can make the two most important parameters that guarantee the success of surgical prostheses in general and , in particular, surgical hip resurfacing prostheses, i.e., predictability and stability, and thus offer alternatives and innovative techniques for the design and manufacture of anti-dislocation surgical prostheses for hip resurfacing in non-metallic materials, was developed at hip in multidense porous ceramic with functional gradient.

[14] The referred anti-dislocation surgical prosthesis of hip resurfacing in multidense porous ceramic with functional gradient appears as a new technology for orthopedic surgeries of hip resurfacing arthroplasty, where its functional safety characteristics eliminate the common negative situations offered by metallic prostheses similar ones found on the market today, regarding situations where the immune response of debilitated individuals who are candidates for hip arthroplasty puts the post-surgical stability of the prosthesis at risk.

[15] In addition, the new Functional Gradient Multidense Porous Ceramic Hip Resurfacing Anti-Dislocation Surgical Prosthesis for Human Hip Arthroplasty, which is also suitable for animals of any size, is designed to be fabricated from non-metallic materials: ceramics and ceramic composites and/or polymeric and polymeric composites.

BRIEF DESCRIPTION OF THE INVENTION

[16] The present invention relates to an anti-dislocation surgical prosthesis in ceramic and/or polymeric, porous and multidense materials and in functional gradient for the recapping of spheroid or condylar ends of long bones; more specifically, it deals with a prosthesis that does not contain metallic materials, capable of lining the ends of bones, such as those of the hip or shoulder of children, young people, adults and the elderly, as well as hip arthroplasty of animals of any size, that present any diseases of these synovial joints, which may, in any case, be used in hospitals, orthopedic and veterinary surgery clinics, or similar institutions; due to its anti-dislocation versatility.

[17] This prosthesis is made up of three parts: the femoral head, which can have different sizes, the femoral pin-guide rod in one size or according to the femoral head, and the pelvic acetabulum, which can have different sizes in correspondence. with the femoral head. The femoral head and the pelvic acetabulum are made of ceramic, porous, multidense and functional gradient materials. The femoral guide-pin rod is made of ceramic or polymeric materials, porous, multidense and in a functional gradient. The femoral head has its outer ceramic part dense and polished and its inner ceramic part, which comes into contact with the bone tissue at the end of the bone, porous, multidense and in a functional gradient. The pelvic acetabulum has its inner ceramic part dense and polished and its outer ceramic part, which comes into contact with the bone tissue of the hip, porous, multidense and in a functional gradient. The femoral guide-pin rod that is inserted into the hole at the end of the bone in hip arthroplasty has a dense core and a multidense porous surface in a functional gradient that is in contact with the bone tissue. This rod in polymeric material can be reinforced or not with carbon fibers.

BRIEF DESCRIPTION OF THE FIGURES

[18] Fig. 1 is a graphical representation of the multidense functional gradient porous ceramic hip resurfacing implanted into a human synovial joint.

[19] Fig. 2 is a graphical representation of the frontal cutaway view of the antidislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient implanted in a canine synovial joint.

[20] Fig. 3A is a cross-sectional graphical representation of the acetabulum of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient.

[21] Fig. 3B is a cross-sectional graphical representation of the head of the antidislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient.

[22] Fig. 3C is a graphical representation of the front sectional view of the guide pin-rod of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient.

[23] Fig. 3D is a graphical representation of the frontal cutaway view of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient, showing its three components, the femoral head, the femoral pin-rod and the hip pelvic acetabulum.

[24] Fig. 4 is a graphical perspective representation of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient, showing its three components, the femoral head, the femoral guide-pin rod and the pelvic acetabulum of the hip, in a synovial joint human.

[25] Fig. 5 is a graphical perspective representation of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient, showing its three components, the femoral head, the femoral guide-pin rod and the pelvic acetabulum of the hip, in a synovial joint canine.

[26] Fig. 6A is a cross-sectional graphic representation showing the insertion of the artificial round ligament system (anti-dislocation lock and suture threads) into the perforation of the acetabular cavity of the pelvis for the fixation of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramic with functional gradient, using the thin end of the tool specially designed to carry out this operation and drilling the anchor or fixing lock.

[27] Fig. 6B is a cross-sectional graphical representation showing the positioning and locking of the anchor or anti-dislocation lock of the artificial round ligament system (anti-dislocation lock and sutures) behind the drilling of the acetabular cavity of the pelvis for the fixation of the anti-dislocation surgical prosthesis for hip resurfacing in multidense porous ceramics with functional gradient, using the thick end of the tool specially designed to carry out this operation.

[28] Fig. 6C is a cross-sectional graphic representation showing the anti-dislocation surgical prosthesis for hip resurfacing in functional gradient porous multidense ceramic, positioned and locked or anchored through the artificial round ligament system (anti-dislocation lock and sutures) in the acetabular cavity of the pelvis.

DETAILED DESCRIPTION OF THE INVENTION

[29] The present invention relates to an anti-dislocation surgical prosthesis in ceramic and/or polymeric materials, multidense porous and in functional gradient for orthopedic surgeries of arthroplasty of resurfacing of spheroid or condylar ends of long bones, for example, the hip, of humans or animals. As can be seen in Figs. 1 and 2, and 4 and 5, respectively, said prosthesis comprises the following elements: a femoral head (7), (8), a femoral guide-pin rod (9), (10) and a pelvic acetabulum (13 ), (14). The prosthesis was designed with geometry to be used in recapping arthroplasty of spheroid ends of human femurs (1) or animals (2) in hip or shoulder arthroplasty surgeries in young, adult and elderly patients, as well as in hip arthroplasty in animals of any size, as can be seen, respectively, in Fig. 1, for human femurs (1) and Fig. 2 for canine femurs (2).

[30] In Figs. 1 and 2, which illustrate human (1) and canine (2) femurs, respectively, the respective drilling (11) or (12), in turn, where the guide-pin rod (9) or (10) is inserted of the prosthesis and the end modeled in cylindrical shape (5) or (6), respectively, where the femoral head (7) or (8) of the prosthesis is coupled, are similar for any size of prosthesis for humans or animals.

[31] Preparation operations for seating the resurfacing prosthesis are performed with special tools on the bone ends of human femurs (1) and canine femurs (2), and are necessary to safely couple and position the surgical resurfacing prosthesis and accuracy.

Femoral Head of Anti-dislocation Surgical Prosthesis for Humans

[32] The femoral head (7) of the surgical resurfacing prosthesis for humans, as shown in Figs. 1, 3B, 3D and 4, has a dense ceramic structure (21) and its spherical outer surface (23) is polished with high dimensional and shape accuracy. Its inner surface (24), which is in contact with the surface of the modeled bone (5), is porous, multidense and in a functional gradient. The interior porous surface (24) of the femoral head (7) which has a thickness between 0.5 to 2.0 mm can contain, since the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite and bone growth factors such as morphogenetic proteins such as BMP (bone morphogenetic protein) and similar and/or live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues. The femoral head (7) has a housing or cylindrical hole (25) for coupling the femoral guide pin-rod (9) and also chamfers (27) or internal and external finishing rounding.

[33] The femoral head (7) of the resurfacing anti-dislocation surgical prosthesis has a manufacturing process involving two ceramic processes in co-pressing: uniaxial pressing in two stages at 50.0 MPa and isostatic pressing at 200.0 MPa.

[34] The femoral head (7) has a central hole (41), with external countersunk (42) and rounded edges, for the passage of surgical suture threads (19) that simulate and/or replace the round ligament of the joint , which prevent dislocation of the prosthesis. The central hole (41) countersunk in the femoral head (7) coincides with the hole (48) in the pelvic acetabulum (13) for both to allow the passage of surgical threads (19) which constitute a system functionally equivalent to that of the round ligament.

Anti-Dislocation Surgical Prosthesis Femoral Guide-Pin for Humans

[35] The femoral guide-pin rod (9), as shown in Figs. 1, 3C, 3D and 4, has a dense structure (28), and its external surface (29), which is in contact with the internal surface of the hole (11) of the femoral bone (1), is porous, multidense and in functional gradient. The external porous surface (29) of the femoral guide-pin rod (9), which has a thickness between 0.3 to 1.0 mm, may contain, from the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite and bone growth factors such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues. The femoral guide-pin rod (9) is assembled and cemented in the femoral head (7), in the housing or cylindrical hole (25), to form the femoral assembly of the resurfacing anti-dislocation surgical prosthesis, using adhesives or commercial biological cements. The femoral set of the resurfacing surgical anti-dislocation prosthesis for humans, as described, can be manufactured in a single piece formed by the femoral guide pin-rod (9) and the femoral head (7), eliminating the use of adhesives.

[36] The femoral guide-pin rod (9), with a dense body (28) and a multidense porous surface (29) with a functional gradient, as shown in Figs. 1, 3C, 3D and 4 can be manufactured with ceramic or polymeric materials, such as PMMA or similar, reinforced or not with carbon fibers if manufactured with polymeric materials or can be isostatically pressed if manufactured with ceramic materials. In both possibilities, the femoral guide-pin rod (9) of the total surgical resurfacing prosthesis has a dense core (28) and a porous surface (29), multidense in a functional gradient.

[37] The femoral guide-pin rod (9) has a central hole (46), which allows the passage of surgical suture threads (19) that simulate and/or replace the round ligament and that prevent dislocation of the prosthesis. The central hole (46) of the femoral guide-pin (9) coincides with the hole (41) of the femoral head (7) and, in this way, allows the passage of the surgical threads (19) for locking the complete prosthesis ( acetabulum, femoral head and guide rod) through the anchor or latch (17) of the pelvis and the anchor or latch (18) of the femur, with adequate surgical mooring (20) of the surgical threads, after passing through the hole (15) output of the femur, using conventional suture needles (52), thus performing the function of the artificial round ligament system, which positions the prosthesis in its joint function and prevents its accidental dislocation.

Pelvic Acetabulum of Total Resurfacing Surgical Prosthesis for Humans

[38] The pelvic acetabulum (13) illustrated in Figs. 1, 3A, 3D and 4, has a dense ceramic structure (30) and its inner surface (32) is polished with high dimensional and shape accuracy. On the other hand, its external surface (31), which is in contact with the acetabular bone surface of the human hip (3), as shown in Fig. 1, is porous, multidense and functionally gradient. The external porous surface (31) of the pelvic acetabulum (13) has a thickness between 0.5 and 2.0 mm and may contain, since the manufacturing process, osteoinductive materials, such as 45S5 bioglass, hydroxyapatite and bone growth factors , such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues. The pelvic acetabulum (13) may present on its external porous surface, indentations or circular pits with a greater porous thickness and with a concentration of osteoinductive materials also greater, to emulate its fixation, through accelerated osseointegration in these sites of contact with the bone host (3). The pelvic acetabulum (13) has chamfers (33) or internal and external finishing rounding.

[39] The pelvic acetabulum (13) has a manufacturing process involving two ceramic processes in co-pressing: uniaxial pressing in two stages at 50.0 MPa and isostatic pressing at 200.0 MPa.

[40] In addition, the pelvic acetabulum (13) has a central hole (48), countersunk (50) internally with rounded edges, for the passage of surgical suture threads (19) that simulate and/or replace the round ligament, which prevent dislocation of the prosthesis. The central hole (48) of the pelvic acetabulum (13) coincides with the hole (16) of the pelvic bone (3) and both allow the passage and locking of the anchor or latch (17) for fixing the round ligament system constituted by the surgical threads (19).

Round Ligament Equivalent System of Total Resurfacing Surgical Prosthesis for Humans

[41] The artificial system of the round ligament, consisting of two anchors or anti-dislocation locks, the pelvic (17) and the femoral (18) and suture threads (19) of the anti-dislocation surgical prosthesis of resurfacing, as shown in Fig. 1, performs the anti-dislocation function that characterizes the surgical prosthesis of the present invention. The artificial system of the round ligament, as tested on bench models, limits the axial displacement between the acetabulum (13) and the femoral head (7) of the surgical prosthesis within design and functional standards, allowing, however, all other movements joints in the normal range of motion (ROM) of the hip, that is, flexion, extension, medial rotation and lateral rotation, safely and naturally.

[42] For the insertion of the round ligament artificial system, consisting of two anchors or anti-dislocation locks, the pelvic (17) and the femoral (18) and suture threads (19) of the anti-dislocation surgical prosthesis for resurfacing, a tool is used (53) specially designed to perform this operation, which has two ends with different diameters, a thin one (54) to perform the insertion of the anchor or pelvic lock (17) of the system that carries the surgical threads (19), as shown in the figure. Fig. 6A, and a thicker one (55), which positions the pelvic anchor or latch (17), as shown in Fig. 6B, after passing through the hole (16) in the pelvic bone, locking the system equivalent in terms of function to that of the round ligament of the animal hip joint.

[43] Once locked in the pelvis, the artificial round ligament system, through the pelvic anchor or lock (17) and the suture threads (19) of the resurfacing anti-dislocation surgical prosthesis, performs the passage of these suture threads (19) through the femoral head (7) and guide-pin rod (9), already cemented together (glued and forming a single component), through their respective holes (41, 46), using the appropriate conventional surgical needle (52) to this function. The resurfacing anti-dislocation surgical prosthesis, together with the artificial system of the round ligament, is therefore housed in the hole (11) existing in the femur (1), with its porous surface (24) internal to the head coupled to the cylindrical neck (5), already modeled of the femur (1), and its external porous surface (29) of the rod-guide-pin in the femoral hole (11), in a precise and stable fit.

[44] The suture threads (19) are led by the surgical needle (52) through the femur exit hole (15), where it passes through the femoral anchor or lock (18) that receives the external surgical mooring (20), performing thus the function of the round ligament equivalent system, which positions and stabilizes the prosthesis and prevents its accidental dislocation.

Femoral Head of Anti-dislocation Surgical Prosthesis for Dogs and Animals of Any Size

[45] The femoral head (8) of the surgical resurfacing prosthesis for animals of any size, as shown in Figs. 2, 3B, 3D and 5, has a dense ceramic structure (22) and its spherical outer surface (34) is polished with high dimensional and shape accuracy. Its inner surface (35), which is in contact with the surface of the modeled bone (6), is porous, multidense and in a functional gradient. Furthermore, the inner porous surface (35) of the femoral head (8) which has a thickness between 0.5 to 2.0 mm can contain, since the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite; and bone growth factors such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues. The femoral head (8) has a housing or cylindrical hole (26) for coupling the femoral guide pin-rod (10) and also chamfers (27) or internal and external finishing rounding.

[46] The femoral head (8) has a manufacturing process involving two ceramic processes in co-pressing: uniaxial pressing in two stages at 50.0 MPa and isostatic pressing at 200.0 MPa.

[47] In addition, it has a central hole (43), countersunk externally (44) with rounded edges, for the passage of surgical suture threads (19) that simulate and/or replace the round ligament, which prevent dislocation of the prosthesis . The reamed central hole of the femoral head (8) coincides with the hole (49) of the pelvic acetabulum (14) for both to allow the passage of surgical threads (19) that constitute a functional system equivalent to that of the round ligament.

Anti-dislocation Surgical Prosthesis Femoral Guide-Pin for Dogs and Animals of Any Size

[48] The femoral guide pin-rod (10), as shown in Figs. 2, 3C, 3D and 5, has a dense structure (36) ceramic or polymeric or composite and its external surface (37), which is in contact with the internal surface of the hole (12) of the canine femur (2) or animal , is porous, multidense and in a functional gradient. The external porous surface (37) of the femoral guide pin-rod (10) which has a thickness between 0.3 to 1.0 mm can contain, from the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite; and bone growth factors such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues.

[49] The femoral guide-pin rod (10) is assembled and cemented into the femoral head (8), in the cylindrical housing (26) , to form the femoral set of the anti-dislocation surgical prosthesis for resurfacing animals of any size, using adhesives or commercial biological cements. The femoral set of the anti-dislocation surgical prosthesis for resurfacing animals of any size, as described, can be manufactured in a single piece formed by the femoral guide-pin rod (10) and the femoral head (8), eliminating the use of adhesives.

[50] The femoral guide-pin rod (10), with a dense body (36) and a multidense porous surface (37) with a functional gradient, as shown in Figs. 2, 3C and 3D can be manufactured from ceramic or polymeric materials and can be molded with or without carbon fiber reinforcements if manufactured from polymeric materials or will be isostatically pressed if manufactured from ceramic materials. In both possibilities, the femoral guide-pin rod (10) has a dense core (36) and a porous surface (37), multidense in a functional gradient.

[51] In addition, the femoral guide-pin rod (10) has a central hole (47), which allows the passage of surgical suture threads (19) that simulate and/or replace the round ligament, preventing dislocation of the prosthesis. The central hole of the femoral guide-pin (10) coincides with the hole (43) of the femoral head (8) and, thus, both allow the passage of surgical threads (19) for locking the complete prosthesis (acetabulum, femoral head and guide-pin rod) through the anchor or latch (17) of the pelvis and the anchor or latch (18) of the femur, with adequate surgical mooring (20), after passing through the hole (15) for exiting the femur ( 2), using suture needles (52), thus performing the function of an artificial round ligament system, which positions the prosthesis and prevents its accidental dislocation.

Pelvic Acetabulum of Total Surgical Resurfacing Prosthesis for Dogs and Animals of Any Size

[52] The pelvic acetabulum (14) of the resurfacing anti-dislocation surgical prosthesis illustrated in Figs. 2 and 3A have a dense ceramic structure (38) and its inner surface (40) is polished with high dimensional and shape accuracy. Its outer surface (39), which is in contact with the bone surface of the canine or animal hip (2), as shown in Fig. 2, is porous, multidense and functionally gradient. The external porous surface (39) of the pelvic acetabulum (14) has a thickness between 0.5 to 2.0 mm and may contain, since the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite; and bone growth factors such as morphogenetic proteins such as BMP and the like and/or with live bone and/or cartilaginous tissue cultures precultured in co-culture of these tissues.

[53] The pelvic acetabulum (14) may present on its external porous surface, indentations or circular pits with a greater porous thickness and with a concentration of osteoinductive materials also greater, to emulate its fixation, through accelerated osseointegration in these contact sites with the host bone (2) . In addition, the pelvic acetabulum (14) has chamfers (33) or internal and external rounding for finishing and has a manufacturing process involving two ceramic processes in co-pressing: uniaxial pressing in two stages at 50.0 MPa and isostatic pressing at 200.0 MPa.

[54] The pelvic acetabulum (14) has a central hole (49), countersunk (51) internally with rounded edges, for the passage of surgical suture threads (19) that simulate and/or replace the round ligament, which prevent the prosthesis dislocation. The central hole of the pelvic acetabulum (14) coincides with the hole (45) of the pelvic bone (4) and both allow the passage and locking of the anchor or lock (17) for fixing the round ligament system constituted by the surgical threads (19) .

Total Surgical Resurfacing for Dogs and Animals of Any Size

[55] The artificial system of the round ligament, consisting of two anchors or anti-dislocation locks, the pelvic (17) and the femoral (18) and suture threads (19) of the anti-dislocation surgical prosthesis of resurfacing, as shown in Figs. 2 and 6C, perform the anti-dislocation function that characterizes the surgical prosthesis of the present invention. The artificial system of the round ligament, as tested on bench models, limits the axial displacement between the acetabulum (14) and the femoral head (8) of the surgical prosthesis within design and functional standards, allowing, however, all other movements joints in the normal range of motion (ROM) of the hip, that is, flexion, extension, medial rotation and lateral rotation, safely and naturally.

[56] For the insertion of the round ligament artificial system, consisting of two anchors or anti-dislocation locks, the pelvic (17) and the femoral (18) and suture threads (19) of the surgical prosthesis, a tool (53) is used. specially designed to carry out this operation, which has two ends with different diameters, a thin one (54) to perform the insertion of the anchor or pelvic lock (17) of the system that carries the surgical threads (19), as shown in Fig. 6A, and a thicker one (55), which positions the pelvic anchor or latch (17), as shown in Fig. 6B, after passing through the hole (45) in the animal pelvic bone, locking the system equivalent in terms of function to the round ligament of the animal hip joint.

[57] Once the artificial round ligament system is locked in the animal pelvis through the pelvic anchor or lock (17) and the suture threads (19) of the resurfacing anti-dislocation surgical prosthesis, the passage of these suture threads is performed (19) through the femoral head (8) and guide-pin rod (10), already cemented (glued and forming a single component), through their respective holes (43, 47), using a surgical needle (52) suitable for this function.

[58] The resurfacing anti-dislocation surgical prosthesis, together with the artificial round ligament system, is therefore housed in the hole (12) existing in the animal femur (2), with its porous surface (35) internal to the femoral head coupled to the neck cylindrical (6), already modeled from the animal femur (2), and with the outer surface (37) of the femoral guide-pin attached to the femoral hole (12), in a precise and stable fit.

[59] The suture threads (19) of the resurfacing anti-dislocation surgical prosthesis are guided by the surgical needle (52) through the femur exit hole (15), where it passes through the femoral anchor or lock (18) that receives the mooring ( 20) external surgery, thus performing the function of the round ligament equivalent system, which positions and stabilizes the prosthesis and prevents its accidental dislocation.

[60] As can be seen, all the porous surfaces of the components of the anti-dislocation surgical prosthesis in ceramic, polymeric, metallic, composite and similar materials for orthopedic surgeries of hip resurfacing arthroplasty have a functional gradient, inherent to their manufacture and can receive compositions of bioglass, hydroxyapatite, or similar bone growth accelerators and/or live bone and/or cartilaginous tissue cultures pre-cultivated in co-culture of these tissues, which guarantee their mechanical behavior and their biological integration in the form of a multidense porous matrix to maintain its stability as a resurfacing hip prosthesis.

[61] Its multidense porous surfaces with functional gradient have a porous structure with active pores with dimensions between 50.0µm to 400.Oµm to ensure bone integration through its adhesion to the site of bone repair, allowing cell growth depending on the their pores have characteristics and dimensions recommended by the literature. Therefore, the choice of materials in this patent is confirmed, which combine properties of biocompatibility, dimensional and functional stability, chemical stability and mechanical resistance, such as those inherent to ceramics or polymers or metals, objects of the present invention.

[62] Although the invention has been widely described, it is obvious to those skilled in the art that various changes and modifications can be made to improve the design without said changes falling outside the scope of the invention.

Claims:

1. Anti-dislocation surgical prosthesis for use in humans or animals of any size comprising a femoral head (7, 8), femoral guide-pin rod (9, 10) and pelvic acetabulum (13, 14), characterized by the fact that the femoral head (7, 8) has a central hole (41, 43), with an external countersunk (42, 44) and rounded edges, has a dense ceramic structure (21, 22) and its outer surface (23, 34) is spherical and polished with high dimensional and shape precision and its interior surface (24, 35) is porous, multidense and in a functional gradient, such head (7, 8) being coupled respectively to the end modeled in the cylindrical shape (5, 6); a femoral guide pin-rod (9, 10) with a dense structure (28, 36) and external surface (29, 37) porous, multidense and in a functional gradient, which is in contact with the internal surface of the hole (11, 12 ) of the femoral bone (1, 2), which has a central hole (46) that coincides with the hole (41) of the femoral head (7) for the passage of surgical suture threads (19) in order to promote locking through of the anchor or latch (17) of the pelvis and the anchor or latch (18) of the femur, with surgical mooring (20) of the surgical threads after passing through the hole (15) at the exit of the femur using conventional suture needles (52) and a pelvic acetabulum (13, 14) that has a dense ceramic structure (30, 38), an external surface (31, 39) porous, multidense and in functional gradient that is in contact with the acetabular bone surface of the hip (3, 2 ) and an internal structure (32, 40) polished with high dimensional and shape accuracy. 

2. Prosthesis, according to claim 1, characterized by the fact that the central hole (41, 43) reamed of the femoral head (7, 8) coincides with the hole (48, 49) of the pelvic acetabulum (13, 14). 

3. Prosthesis, according to claim 1, characterized in that the inner porous surface (24, 35) of the femoral head (7, 8) has a thickness between 0.5 to 2.0 mm and contains, from the process manufacture, osteoinductive materials such as 45S5 bioglass and hydroxyapatite and bone growth factors such as morphogenetic proteins such as BMP (bone morphogenetic protein) and similar and/or live bone and/or cartilaginous tissue cultures precultured in coculture of these tissues. 

4. Prosthesis, according to claim 1, characterized by the fact that the femoral head (7, 8) has a housing or cylindrical hole (25, 26) and chamfers (27) or internal and external rounding. 

5. Prosthesis, according to claim 1, characterized in that the external porous surface (29, 37) of the femoral guide-pin rod (9, 10) has a thickness between 0.3 and 1.0 mm and contains , from the manufacturing process, osteoinductive materials such as 45S5 bioglass and hydroxyapatite; and bone growth factors such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in coculture of these tissues. 

6. Prosthesis, according to claim 1, characterized by the fact that the femoral guide-pin rod (9, 10) is manufactured with polymeric or polymeric ceramic materials. 

7. Prosthesis, according to claim 6, characterized by the fact that the femoral guide-pin rod (9, 10) when manufactured with polymeric materials is reinforced with carbon fibers. 

8. Prosthesis, according to claim 6, characterized by the fact that the femoral guide-pin rod (9, 10) when manufactured with ceramic materials is isostatically pressed. 

9. Prosthesis, according to claim 1, characterized in that the femoral guide pin-rod (9, 10) has a central hole (46, 47) that coincides with the hole (41, 43) of the femoral head ( 7, 8). 

10. Prosthesis, according to claim 1, characterized in that the external porous surface (31, 39) of the pelvic acetabulum (13, 14) has a thickness between 0.5 and 2.0 mm and contains, from the process manufacturing, osteoinductive materials, such as 45S5 bioglass, hydroxyapatite; and bone growth factors, such as morphogenetic proteins such as BMP and the like and/or live bone and/or cartilaginous tissue cultures precultured in coculture of these tissues. 

11. Prosthesis, according to claim 1, characterized by the fact that the external porous surface (31) of the pelvic acetabulum (13, 14) presents indentations or circular pits with a greater porous thickness and with a concentration of osteoinductive materials also greater. 

12. Prosthesis, according to claim 1, characterized by the fact that the pelvic acetabulum (13, 14) has chamfers (33) or internal and external finishing rounding. 

13. Prosthesis, according to claim 1, characterized in that the pelvic acetabulum (13, 14) has a central hole (48, 49), internally countersunk (50, 51) with rounded edges, which coincides with the hole ( 16, 45) of the pelvic bone (3, 4). 

14. Artificial round ligament system of the prosthesis as defined in any one of claims 1 to 13, characterized in that it comprises the pelvic (17) and femoral (18) anti-dislocation anchors or locks (18), suture threads (19) and a tool ( 53) with a thin end (54) and a thick end (55). 

15. System according to claim 14, characterized in that it limits the axial displacement between the acetabulum (13, 14) and the femoral head (7, 8) of the surgical prosthesis and allows normal hip joint movements. 

16. System, according to claim 14, characterized in that the suture threads (19) are conducted by a conventional surgical needle (52) (52) through the femoral head (7, 8) and guide-pin rod (9 , 10) already cemented together through their respective holes (41, 43, 46, 47). 

17. System, according to claim 14, characterized in that the suture threads (19) are led by the surgical needle (52) through the hole (15) at the exit of the femur, where it passes through the femoral anchor or lock (18 ) that receives the external surgical tie (20). 

18. System according to any one of claims 14 to 17, characterized in that together with the surgical prosthesis it is housed in the hole (11, 12) in the femur (1, 2), with a porous surface (24, 35 ) inside the head coupled to the cylindrical neck (5, 6), already modeled from the femur (1, 2), and its external porous surface (29, 37) of the guide-pin rod in the femoral hole (11, 12), in accurate and stable adjustment. 










 

External links

Purquerio BM, Fortulan CA, Botega R, de Moraes TF. Prótese cirúrgica antiluxação e sistema artificial de ligamento redondo da mesma [Antiluxation surgical prosthesis and artificial round ligament system thereof]. BR102015006381B1 March 23, 2015. 2023. patents.google

 

Authors & Affiliations

Benedito De Moraes Purquerio – De São Paulo, BR

Renan Botega – De São Paulo, BR

Thiago Francisco De Moraes – De São Paulo, BR

Carlos Alberto Fortulan – De São Paulo, BR

 

Keywords

ligamentum capitis femoris, ligamentum teres, ligament of head of femur, endoprosthesis, prosthesis, invention, bipolar, total


                                                                     

NB! Fair practice / use: copied for the purposes of criticism, review, comment, research and private study in accordance with Copyright Laws of the US: 17 U.S.C. §107; Copyright Law of the EU: Dir. 2001/29/EC, art.5/3a,d; Copyright Law of the RU: ГК РФ ст.1274/1.1-2,7


ENDOPROSTHESES AND IMPLANTS




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